Tris Base is a widely used organic reagent. It and its derivatives are extensively applied in the preparation of buffers for biochemistry and molecular biology experiments, and can be used in pharmaceutical production, organic synthesis, biological buffers, etc. The disclosure of Moderna's COVID-19 vaccine formula shows that Tris can serve as an excellent buffer for mRNA-LNP complexes, which has aroused people's attention and interest in Tris as a buffer system for protein or nucleic acid drugs.

Adhering to its consistent concept of high quality, Pfanstiehl launched the injectable-grade Tris Base (Product No.: T-153) in November 2023. This product features high purity, ultra-low endotoxin, and ultra-low residual metal impurities. Additionally, it incorporates detection for multiple new quality indicators, including DNA, RNA, DNase, RNase, and lipase. It complies with the regulations of multiple pharmacopoeias (USP, EP, BP, ChP) and can be used in the production of biotherapeutic drugs and vaccines.

Product Information

· Product Name: Tris Base, High Purity, Low Endotoxin, Low Metals

· Chinese Name: 三羥甲基氨基甲烷 (Sanqiangjiaji Anjijiawan)

· Molecular Formula: C?H??NO?

· Molecular Weight: 121.14 g/mol

· CAS No.: 77-86-1

· Product Code: T-153

Product Features

· High purity, ultra-low endotoxin, ultra-low microbial content, and ultra-low residual metal impurities

· Newly added detection of quality indicators: DNA, RNA, DNase, RNase, and lipase

· Complies with multiple pharmacopoeias: USP, EP, BP, ChP

· Complies with ICH Q3D standard

· Complies with GMP standards

· CDE Registration No.: F20240000172

Product Application

· Buffer

Pfanstiehl Inc. offers a full range of products. For a free 100g sample, please contact Beijing XMJ Technology Co., Ltd., the authorized distributor of Pfanstiehl in China.